Therapeutic Angiogenesis With Autologous Hepatic Tissue Implantation and Omental Wrapping
نویسندگان
چکیده
منابع مشابه
Therapeutic angiogenesis with autologous hepatic tissue implantation and omental wrapping.
BACKGROUND The liver produces various angiogenic and cytoprotective growth factors and the omentum has potent angiogenic properties that promote wound healing. The ability of hepatic tissue implantation plus omental wrapping to induce angiogenesis and restore cardiac function was investigated in a rat model of infarction. METHODS AND RESULTS Myocardial infarction was induced in rats using cor...
متن کاملAutologous bone marrow cell implantation as therapeutic angiogenesis for ischemic hindlimb in diabetic rat model.
The angiogenic effect induced by autologous bone marrow cell implantation (BMCI) was examined in the ischemic hindlimbs of diabetic and nondiabetic rats. Diabetes mellitus was induced by the systemic administration of streptozotocin. We investigated the production of angiogenic factors and endothelial differentiation from bone marrow cells and the native recovery of blood flow in the ischemic h...
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OBJECTIVE We previously reported a novel technology for the engineering of a capillary network using an optical lithographic technique. To apply this technology to the therapy of ischemic diseases, we tested human omental microvascular endothelial cells (HOMECs) as an autologous cell source and decellularized human amniotic membranes (DC-AMs) as a pathogen-free and low immunogenic transplantati...
متن کاملCombination of in vivo angiopoietin-1 gene transfer and autologous bone marrow cell implantation for functional therapeutic angiogenesis.
OBJECTIVE Autologous bone marrow mononuclear cell (BM-MNC) implantation into ischemic tissues promotes angiogenesis, but a large amount of marrow aspiration is required, which is a major clinical limitation. Angiopoietin-1 (Ang-1) is requisite for vascular maturation during angiogenesis. We examined the impacts of combinatorial Ang-1 gene transfer and low-dose autologous BM-MNC implantation on ...
متن کاملImplantation for Functional Therapeutic Angiogenesis Combination of In Vivo Angiopoietin-1 Gene Transfer and Autologous Bone Marrow Cell
Koichi Kobayashi, Takahisa Kondo, Natsuo Inoue, Mika Aoki, Masaaki Mizuno, Kimihiro Implantation for Functional Therapeutic Angiogenesis Combination of In Vivo Angiopoietin-1 Gene Transfer and Autologous Bone Marrow Cell Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2006 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the Ame...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2008
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-08-0167